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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c8aa851ec03066f65fb9df97ebd00dfb01d82d750272ff635477de259e1ea4' 
  AND token = '0FK+49bBrl7UbpJLJKhuPIpWsKlptepyXFOsTVqIAKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}