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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2635f9b1d89e965efbf23b830d7f483be79a6ca4051bdcecf1d04a22a0525def' 
  AND token = 'OOhZ39YCnaBs+eldZ8VSG23jiegCrLJZruPki1BAbB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}