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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec48972f3d535ff7906d3e1984c672760f577996d0ce08e7374eef26ddf1adbc' 
  AND token = 'qctIYjsLjjwrHSTtpLS9mP8rgAWQMgRKcJVmmlRSbWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}