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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b58fa8400d4b957eb0fe1092257cc0bfb161e3e792d03fbe0ebe7cf7e22af83' 
  AND token = 'Ifo1yKFJ+MSjJg0aR7sKdXl6F42+BnqOz/XSZps9dZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}