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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dfeb3b3e1d9516c32c92eb50abe0283b78e1ad4254a63e655940d34ee249c0d' 
  AND token = 'MXrUgr7TvTV1oDSWWdfDnqlDqBfdQL3WE/nA2aiucnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}