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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f789b812c349e8581e5f882ba08ee45d68677b11e758696e3accc0db6bab12c' 
  AND token = 'sg9hH715eB66wnwB5nXz1KmlexLHgBs9Wa2SmItZif0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}