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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065f84dffb0129dd4396cb7f6de7b8b2ea9e4d239c1312f0474bac83453afeae' 
  AND token = '363gzZtwdQuWplhfwgL+RvsFu5XOmcO3emfb2jeoeCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}