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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77d5b89bf85ea1af69209e09e0c65834f45bf418e0d607c6a5bbf4b27cd50bc2' 
  AND token = 'bXuEIAdkxoXS2OIE2ziUIwM93Bsw2lGuYLQudXK3PQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}