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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47116ea0ed806d61ec1fc360c4c825e396feb902b499b9d6c9b53f865db3deee' 
  AND token = 'RRp/pFVawbdSzDUQ1jmmR17ihq8k9pAe8hoeYSME8Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}