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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3b2949b6d645e55d321a64f9d4cbd04d5bc6f6209706c2324cfb0b75d3c303b' 
  AND token = '+8Ele5B4DeAy9wSYlpZ4wnphXKQHno/4U591HAKxH4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}