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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4cee6ff78e21d16a1d9668712ed5ad620f5c4e0dda3a075e50c50ad17dad358' 
  AND token = 'o7dfDtrIay5X3FFXEZTTN0LVJ3z3VfJYXHAh6xSXnFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}