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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5436270ba30b4aeb8da1c3b79dc3fe4851f3283b0d39b8c5661fdb3159ec9753' 
  AND token = 'XIV+Z0opGQBn/+PbmFN+uVUi8ci1iLUVX0uSrICOyU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}