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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4aec9d9ae75d8e1139fb30f022bde059154aa80c5494260b3aa60ef01b936a3' 
  AND token = 'Ej2CUu8Bjdv1GtbKpQ6yPK3tTfu+mmJcobFw4JLPBVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}