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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '388c2b198925683d19aae608982eab281ca55c47ff5a17f7b94eeaed69c2a2e3' 
  AND token = '95eg90v714zoeI02pLGReCYace+LG8VgYzvunStT8m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}