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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d0dd940d05f59792a1245eeca838c383a2d9fe152571d4f9cf8f4db986e6032' 
  AND token = 'eJ9sVl9fhxqtNFQxGhPS9BGcKnoVhxD2oIEJXSlQzuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}