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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2521bef4d71a49e06f2509c7ec8e959f16b54745434500700214978b3f99ce1d' 
  AND token = '5t0EcuqRfeCoj4zrR3Qzdf+DNbai7d1sLGkuMYJJY8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}