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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d89c7d7668d76915bec7c12cb7dbfc4ef1db6e7622b3da059bb2a81f101812a' 
  AND token = 'etePsrAR9z2uzRfFo6NuE19HGa+xDCuo5Sggm0hzB4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}