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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2e7b1555cb9277ba7ab170f72eb44893c7890a06eeadb6c9ad5137aec34b0f' 
  AND token = 'JH7RIUTg2ERrmQO3i07Ip4efNz5HTkYhkYnCxxHxXvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}