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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f141a9678cadf15eebfe1fe03a070684e7f22d0655b3913b3dfec92f7cc997' 
  AND token = 'jQtNIskBMluiEUP/H3GscUlYUZHGcLv2mU9VUksDvfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}