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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c2d139f381c7e89ec5449af8db93fb648ce32b413886cefa47c6cdaa1c5cd50' 
  AND token = '5kDlhMc0PXbU1l76tmeSL+DRlouLl7xO1ZGU0+2UQvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}