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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '999213445f5a7860d02b1b1fdbbc3ae4c9b8e03dfa48a2546ab89e8085a91cc2' 
  AND token = 'HFiuo0c3iE4tsNDzRvSgrSb48dZR0O2PvnKpl6HsK7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}