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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc488a5ad6e82669eb63d61de39efc398be1335118e64e0a9fc07f9bb05c51d' 
  AND token = 'UvdcADcqDqba6V9Q+DHNq6kZVaix98Hil7zcO57LMEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}