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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '025c9125581ccc0527e2e698b5dba416d00515c0098152ecc890e56bb845f8d4' 
  AND token = 'KdOIszAMiDJ+S1FU9HW99MMk6Y2rDXqtqvs8HfK+bBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}