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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3afe4721bfcc5b173685cc4150ed66de0d2bbcedf13c2c8a4e7f4ce103ec6d' 
  AND token = '5AO3hogi9GkVln1dYW+CtkdOkKT9My6LvrekAj2K16o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}