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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e17a09d3d28e32e59a5c899b3bdef4f8cca88e975554e21b76cd5cee3e5f53c' 
  AND token = 'OqFhUTR5XPojvcK03A4lW50VAEZ9rFph2S4x6YOqW5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}