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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23cb9e05f019625b5d8fc1107e942ce14a822d4b1d726bbc315d01366fd72547' 
  AND token = 'mktC008aY12NHkqPYUxwv+eURvuAnatSKXBqsbui9tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}