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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3cf4bf8a6472cc30e421c7303e68be4466b100e6f62b0e250f6a620364fc168' 
  AND token = 'mFO61QGLTEXO+NbUolrwTy5IAM0K7MwszZN34r25ux0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}