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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b4b2ccecd61cbdd541f179c3a1ed8196b5d4e7bcef46fda7848536287dcea73' 
  AND token = 'wb2s2P4gvUi+3iBbJgzkt8WzBLQzlqpzmtK0E6vaSg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}