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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf8435428da5f8bd5e8cdf7f81998a1095fe497b0f60ce80e2b869526f76c95' 
  AND token = 'J47oI9PdeP+thPO+jmHPqsWM2e/wMBO/9qoWmNXjnJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}