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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f765db1b7ec8a5263fa47255c8d3f3e31106d0c72e6b3c528149a1e34cf42959' 
  AND token = '1DXp63QBTCQuTcRlL8DlLosziI4DH9wWRCEQt1sR/LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}