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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95b9a415d3a2be4074b621b8d8bbf0ce9ca8265003c8122553a49b43d38b5ba' 
  AND token = 'do1yvhXrl+JBZCQjPrEFvpUkaD0o8Zn9IcDvJyD5ywI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}