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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280576823d7986a6f13294780693b3d93c0fb4793676ef504cede7bede426b9a' 
  AND token = 'bUfZZNhvLHkGXYrtUFVLeiNezv8CAScxIq50MHx5Lng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}