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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100883a12e0b98581e9474d62b791dd4c382b6b5116e7118467f846cb67f1f52' 
  AND token = 'dznymV/lbNQKWb+nVE6k0gd6lK9b2+iKaUtljWj9Xkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}