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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9339205fc90bc1d0028f8870c17fb464c3cc99611029fcdf21c74b8ba8b7341' 
  AND token = 'TDCMSIvnnxe+YnQsf+MvCreR8/U3brwCpt/vtMJ6HGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}