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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bc1cb2852c35324848fd8c27648ac099d1769ea05e9fdc1d467c7d494ebe574' 
  AND token = '0is1Gtrp3I75kdtq5JPykDwJ2nQTQVL0zbwdRz8zfFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}