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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff69e2176d5e8b5ae2545942499e627f9bf96f701795e48424654c6b8c72040' 
  AND token = 'umyH3/I+f2pbLKiZJOfNAjvB6kDkJBIZIGoj46fC2AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}