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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953a2846ef58e2cb15942ed401b2655ef519a8fba5d6337341a7bada18b0b28d' 
  AND token = 'HQ50OlPaiQNaBE0Ardpd9YzOiagcl1h4MIJOVZWw5Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}