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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13f07a94429b5c0880eb2366e542f8f2a39631fca1dc6dc5d6471a26427d01c8' 
  AND token = 'Lpq9uVQkXCZiT/Wc5AQ0IAM4bfUQmrMNCJya8PUWKm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}