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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd04293880bf73f020e16b5a8bfdcb6a3e4242e530bb00142ee500685f45245bc' 
  AND token = 'EOrT8InX6qxItsTU89NsAPupi4/aXK13yZ0RVHfhjS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}