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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '536d79aed8b415cb92fc10140f1f9882d1433c53e4e9c89538556c1bd750ae90' 
  AND token = 'mESWc901OJd8i6MQ2R7trh2RtiKmUMM09r3B+czC1JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}