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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406507891ad8fda8092e0b386a44d5a3d39138a67dc1fda508948ef0bd44353e' 
  AND token = 'icFVoSerQxmgHXbwsRIIxX47RPEEtIv90HMJ89oLVSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}