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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1fe01a2f23153aab929cb0d8885ccb0de3a788c619a38807a47d346f94841cf' 
  AND token = 'BDE9/2FeWnnI/G1sx5rIzxzS97dXopOJ8alTBoi++Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}