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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318d268ac80d4aadf2b44b1637acf0d8faf822caaa16764c0740d63883af4899' 
  AND token = 'o/hg3CpxEGVSYpM2gj26fMHLg38qSBD5rq1esUlyNTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}