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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250c19b435c2e730f6b8b6070790461246d3db539dcc81f5cfc5d8a6c9dd8130' 
  AND token = 'Rgx7/FjbNmpe1t8qPNNRQ6dwCKVHHYIelP52vVI7XUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}