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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a2ba85f790ee17536c7ea3b288227646d5c51f690ff5e976872aea085575f9' 
  AND token = 'TTfxz1MW0srjvCXx3DGbYdCp9trdOI64RaEZp5zBcWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}