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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '081b15ae71d70bc4fe1949aa38f0a910db5f8e9962d18c04d4639357cdaf9ad2' 
  AND token = 'uHeEMbepdjfXEG0uMGrpzgGQopAmH3ArDtqyLE9Ag4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}