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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b68b60ace76b5ef80dda2738c01c350056a78bcf0a0f0acea66e38bb47caaa5' 
  AND token = '0VkwdkRzcsLjNK1VeEms92eJ+z9sPsAlTtL0pxZcdpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}