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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd358ae9c6cc85ece5043c7547d3cf66bdac78a6e830ffa0246d6612344bc1c4d' 
  AND token = 'H2ovEm9Wh0kIQDAWvQOGUrD6VyQOTNySr82uwbOmqo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}