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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad140f80c1b7ceb9bdb99031b851dfca1fa0b49cf914a8e5c996da016be0773e' 
  AND token = 'Fs88SnzjM5DBTcnwwaA3WreaebnizPXARWumtwzfpAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}