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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d244e7ae5bc9d4bfc6ea36c421fb6c13c0f73dd1830c1801c8cc765379289cf' 
  AND token = 'kKc0KaNXcU2pZKwlCGELK33mKiWZXlEwMc+WW1lanFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}